DiabeticANDAmputation-FNL

Over 29 million Americans, or roughly 10% of the population, are afflicted with diabetes mellitus (DM) which carries a sum of $245 billion in health-related costs. Over one quarter of those individuals are undiagnosed and therefore at risk for severe complications. Surprisingly, up to 25% of diabetic patients carry a lifetime risk of developing a diabetic foot ulcer, a condition plagued with poor healing, infections and ultimately, amputation. 1 Diabetics often suffer comorbidities such as peripheral vascular disease and neuropathy which gives way to the rapid and insidious development of foot ulcers. In the individuals whom remain untreated, 30% will require a lower limb amputation, and a staggering 50% of these amputees die within 5 years of surgery. 2 We are developing a device that allows the physician to process extracted fat, thus creating an enhanced stem cell product that can be reinjected in common areas where ulcers form. If a diabetic foot ulcer has already formed, there is compelling evidence that our therapeutic can be injected in and around the wound to speed healing.3,4